The DNA preparation procedure begins with the collection of a tiny piece of tissue from an anaesthetised mouse. This tissue sample is then broken down to release DNA fragments that can be used to determine the genotype of the animal.
DNA preparation at ABR is carried out using a purpose built robot, enabling the processing of 192 samples at a time. The DNA prepared at ABR is then sent direct to research labs or to the Garvan Institute’s mouse genotyping service (ACRF) where PCR analysis is used to determine the genotype of each mouse. This high tech, high throughput process provides rapid genotype results.
The cost of DNA preparation can be found in the Downloads section and further information on the mouse genotyping service is available at http://linkage.garvan.unsw.edu.au/ACRF/mouse_genotyping.html
|